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Team Effort by TRAPP Forces a Nucleotide Fumble

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Presentation on theme: "Team Effort by TRAPP Forces a Nucleotide Fumble"— Presentation transcript:

1 Team Effort by TRAPP Forces a Nucleotide Fumble
Ryan M. Nottingham, Suzanne R. Pfeffer  Cell  Volume 133, Issue 7, Pages (June 2008) DOI: /j.cell Copyright © 2008 Elsevier Inc. Terms and Conditions

2 Figure 1 Multiple TRAPPI Subunits Promote Nucleotide Release from Ypt1p Model of the TRAPPI subassembly in complex with the Ypt1p GTPase (yellow). The pseudo wedge of Bet3p (purple) can be seen pointing into Ypt1p's nucleotide-binding pocket (enlargement at right). Note how multiple subunits hold Ypt1p open to enhance nucleotide release. Cell  , DOI: ( /j.cell ) Copyright © 2008 Elsevier Inc. Terms and Conditions

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