Presentation is loading. Please wait.

Presentation is loading. Please wait.

Degree of Predicted Minor Histocompatibility Antigen Mismatch Correlates with Poorer Clinical Outcomes in Nonmyeloablative Allogeneic Hematopoietic Cell.

Similar presentations


Presentation on theme: "Degree of Predicted Minor Histocompatibility Antigen Mismatch Correlates with Poorer Clinical Outcomes in Nonmyeloablative Allogeneic Hematopoietic Cell."— Presentation transcript:

1 Degree of Predicted Minor Histocompatibility Antigen Mismatch Correlates with Poorer Clinical Outcomes in Nonmyeloablative Allogeneic Hematopoietic Cell Transplantation  Malene Erup Larsen, Brian Kornblit, Mette Voldby Larsen, Tania Nicole Masmas, Morten Nielsen, Martin Thiim, Peter Garred, Anette Stryhn, Ole Lund, Soren Buus, Lars Vindelov  Biology of Blood and Marrow Transplantation  Volume 16, Issue 10, Pages (October 2010) DOI: /j.bbmt Copyright © 2010 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Probability of OS (A) and cumulative incidence of TRM (B) stratified according to the median number of nsSNP differences in the GVH direction. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2010 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Histograms showing the distribution of patients by number of observed nsSNP differences in the GVH direction (A) and by number of predicted miHAs in the GVH direction (B). MUD, matched unrelated donor; MRD, matched related donor. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2010 American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Probability of OS (A) and cumulative incidence of TRM (B) stratified according to the median number of predicted miHAs in the GVH direction within a patient–donor pair. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2010 American Society for Blood and Marrow Transplantation Terms and Conditions

5 Figure 4 Probability of OS stratified according to number (0, 1-2, or >2) of predicted miHAs in the GVH direction. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2010 American Society for Blood and Marrow Transplantation Terms and Conditions


Download ppt "Degree of Predicted Minor Histocompatibility Antigen Mismatch Correlates with Poorer Clinical Outcomes in Nonmyeloablative Allogeneic Hematopoietic Cell."

Similar presentations


Ads by Google