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Figure 4 11C-PK11195-PET scans showing the evolution of neuroinflammation in a patient after stroke
Figure 4 | 11C-PK11195-PET scans showing the evolution of neuroinflammation in a patient after stroke. Corresponding 11C-PK11195 (PK11195) binding potential maps (top row) and T2-weighted MRI scans (bottom row) are shown at three time points (day 2, 12 and 30) after stroke. Core stroke and contralateral regions of interest (ROIs) are outlined in red and green respectively. PK11195 uptake is minimal at the first time point, prominent at day 12, and has declined substantially by day 30 in the acute infarct region, shown in the corresponding T2-weighted MRI scans at the same time points. Images are in radiological format. Scale bar: tracer binding intensity. Image courtesy of Dr C. J. Price. Image courtesy of Dr C. J. Price. Evans, N. R. et al. (2017) PET imaging of the neurovascular interface in cerebrovascular disease Nat. Rev. Neurol. doi: /nrneurol
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