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Nanopore Sequencing: Forcing Improved Resolution

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Presentation on theme: "Nanopore Sequencing: Forcing Improved Resolution"— Presentation transcript:

1 Nanopore Sequencing: Forcing Improved Resolution
Derek Stein  Biophysical Journal  Volume 109, Issue 10, Pages (November 2015) DOI: /j.bpj Copyright © 2015 Biophysical Society Terms and Conditions

2 Figure 1 Influence of the applied force on the resolution of nanopore DNA sequencing. The schematic shows a DNA strand stalled in the sensitive constriction of an MspA nanopore under (a) a low applied force, which allows diffusion to shuffle the bases in the constriction; and (b) a high applied force, which suppresses fluctuations. To see this figure in color, go online. Biophysical Journal  , DOI: ( /j.bpj ) Copyright © 2015 Biophysical Society Terms and Conditions


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