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Mendelian Genetics Part 2
AP Biology Mendelian Genetics Part 2
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Phenotype by gene expression
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3’ T A C C A G C C G G T A A T A G G G A C C A T T 5’ DNA TEMPLATE
5’ A U G G U C G G C C A U U A U C C C U G G U A A 3’ mRNA METH VAL GLY __ HIST TYR __ PRO TRP __ __ ___ ___ PROTEIN 3’ U A C C A G C C G G U A A U A G G G A C C A U U 5’ ANTI – CODON Sequence Does the DNA Sequence (Million Dollar Blueprint) look like the Anti-codon Sequence? Remember, this is how the ribosome “knew” the Amino Acid was Correct.
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Incomplete Dominance
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Complete Dominance
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Codominance (AB) & Multiple Alleles
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Pleiotropy (Sickle Cell)
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Epistasis BbCc BbCc Sperm BC bC Bc bc BC BBCC BbCC BBCc BbCc bC BbCC
1 BC 1 bC 1 Bc 1 4 4 4 4 bc 1 BC 4 BBCC BbCC BBCc BbCc 1 bC BbCC 4 bbCC BbCc bbCc 1 4 Bc BBCc BbCc BBcc Bbcc 1 bc BbCc bbCc Bbcc bbcc 4 9 3 4 16 16 16
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Dihybrid – Normal 9:3:3:1 ratio
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Polygenic Inheritance & Norm of the Reaction
AaBbCc AaBbCc aabbcc Aabbcc AaBbcc AaBbCc AABbCc AABBCc AABBCC 20/64 15/64 Fraction of progeny 6/64 1/64
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Multifactorial example (Acid in soil changes the color)
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