1. Psoriasis & skin cancer
Giuseppe Argenziano
Clinica Dermatologica,
Università della Campania L. Vanvitelli, Napoli

4. PUVA for 15 years

7. Phototherapy OK… but what about systemic treatments?

8. YES!!!

9. NO!!!

10. YES & NO!!!

11. And what about mortality?

15. In conclusion…
NMSC (not melanoma) is slightly increased by UVB and conventional immune-modulatory treatments but not much by new target therapies
Mortality by circulatory disease is increased but mortality by cancer is actually decreased!!

16. By the way, does psoriasis “per se” favor or protect against skin cancer ?

17. Favor!!!

19. Higher risk for SCC but not BCC… and what about melanoma?

20. YES, more melanomas!!!

21. NO, less melanomas!!!

22. NO, less melanomas!!!

25. Conclusion
Slight increase of SCC but not BCC mainly due to phototherapy
Melanoma seems to be paradoxically less frequent in patients with psoriasis