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Magnetic Resonance vs Transient Elastography Analysis of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Pooled Analysis of Individual.

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Presentation on theme: "Magnetic Resonance vs Transient Elastography Analysis of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Pooled Analysis of Individual."— Presentation transcript:

1 Magnetic Resonance vs Transient Elastography Analysis of Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Pooled Analysis of Individual Participants  Cynthia Hsu, Cyrielle Caussy, Kento Imajo, Jun Chen, Siddharth Singh, Kellee Kaulback, Minh-Da Le, Jonathan Hooker, Xin Tu, Ricki Bettencourt, Meng Yin, Claude B. Sirlin, Richard L. Ehman, Atsushi Nakajima, Rohit Loomba  Clinical Gastroenterology and Hepatology  Volume 17, Issue 4, Pages e8 (March 2019) DOI: /j.cgh Copyright © 2019 AGA Institute Terms and Conditions

2 Figure 1 Distribution of liver stiffness measurements by (A) transient elastography and (B) magnetic resonance (MR) elastography. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions

3 Figure 2 Diagnostic accuracy of transient elastography and magnetic resonance (MR) elastography for diagnosing dichotomized stages of fibrosis. AUROC, area under the receiver-operating characteristic curve. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions

4 Figure 3 Distribution of thresholds value for the diagnosis of dichotomized fibrosis stage of (A) transient elastography and (B) magnetic resonance (MR) elastography. The lower line corresponds to the thresholds for a fixed sensitivity at 90%, line in the middle corresponds to the optimal threshold and the upper line corresponds to the thresholds for a fixed specificity at 90%. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions

5 Figure 4 Magnetic resonance elastography (MRE) and transient elastography (TE) images from representative patients with stage 0, 1, 2, 3, and 4 fibrosis, respectively. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions

6 Supplementary Figure 1 Flow chart summarizing study identification and selection. ARFI, MRE, SWE, TE. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions

7 Supplementary Figure 2 Flow chart summarizing patient exclusion for statistical analysis. MRE, VCTE. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions

8 Supplementary Figure 3 ROC Curve of MRE and TE for the diagnosis of dichotomized stage of fibrosis. Clinical Gastroenterology and Hepatology  , e8DOI: ( /j.cgh ) Copyright © 2019 AGA Institute Terms and Conditions


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