Presentation is loading. Please wait.

Presentation is loading. Please wait.

Regions of sequence homology across dominant clones in TLR7tg animals.

Published byMiles Byrd Modified over 5 years ago

Similar presentations

Presentation on theme: "Regions of sequence homology across dominant clones in TLR7tg animals."— Presentation transcript:

1 Regions of sequence homology across dominant clones in TLR7tg animals.
Regions of sequence homology across dominant clones in TLR7tg animals. (A and B) The CDR3 sequence of the dominant CD8+ T cell clone isolated from the brain of each TLR7tg (n = 8) (A) or spleen of each wild type B6 (n = 8) (B) mouse is shown. The frequency at which each of these top clones appears across all animals is presented. (C) CDR3 alignment along with V, D, and J gene usage for each top clone in TLR7tg or wild type B6 mice. An asterisk (*) indicates an instance in which multiple nucleotide sequences encoding different Vβ genes generated identical CDR3 amino acid sequences. Peter A. Morawski, and Silvia Bolland ImmunoHorizons 2019;3:61-70 ©2019 by American Association of Immunologists

Download ppt "Regions of sequence homology across dominant clones in TLR7tg animals."

Similar presentations

Overlap of the human CD8 + T cell receptor repertoire Harlan S. Robins 1,2, SK Srivastava 1, P Campregher 1, CJ Turtle 1, J Andriesen 2, SR Riddell 1,

Overlap of the human CD8 + T cell receptor repertoire Harlan S. Robins 1,2, SK Srivastava 1, P Campregher 1, CJ Turtle 1, J Andriesen 2, SR Riddell 1,
PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1.

PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1 PfDGAT1-2 AtDGAT1 RcDGAT1 PfDGAT1-1.
By drawing a picture describe the flow of genetic information from DNA to a protein.

By drawing a picture describe the flow of genetic information from DNA to a protein.
MdSFBB3-alpha MSHVRESETPEDRVVEILSRLPPKSLMRFKCIHKSWFSLINNLSFVAKHLSNSVDNKLSSSTCILLNRSQAHIFPDQSWKQEVFWSMINFSIDSDENNLHYDVEDLN-IP 109 MdSFBB3-beta MSQVHESETPEDKVVEILCRLPPKSLMRFKCIRKSWCTLINRPSFVAKHLNNSVDNKLSSSTCILLNRSQAHIFPDQSWKQEVFWSTINLSIDSDEHNLHYDVEDLI-IP.

MdSFBB3-alpha MSHVRESETPEDRVVEILSRLPPKSLMRFKCIHKSWFSLINNLSFVAKHLSNSVDNKLSSSTCILLNRSQAHIFPDQSWKQEVFWSMINFSIDSDENNLHYDVEDLN-IP 109 MdSFBB3-beta MSQVHESETPEDKVVEILCRLPPKSLMRFKCIRKSWCTLINRPSFVAKHLNNSVDNKLSSSTCILLNRSQAHIFPDQSWKQEVFWSTINLSIDSDEHNLHYDVEDLI-IP.
Volume 130, Issue 4, Pages (April 2006)

Volume 130, Issue 4, Pages (April 2006)
MAKRLVLFATVVIALVALTVAEGEASRQLQCERELQESSLEACRLVVDQQLAGRLPWSTGLQMRCCQQLRDISAKCRPVAVSQVARQYGQ MAKRLVLFATVVIGLVALTVAEGEASRQLQCERELQESSLEACRLVVDQQLAGRLPWSTGLQMRCCQQLRDISAKCRPVAVSQVARQYGQ.

MAKRLVLFATVVIALVALTVAEGEASRQLQCERELQESSLEACRLVVDQQLAGRLPWSTGLQMRCCQQLRDISAKCRPVAVSQVARQYGQ MAKRLVLFATVVIGLVALTVAEGEASRQLQCERELQESSLEACRLVVDQQLAGRLPWSTGLQMRCCQQLRDISAKCRPVAVSQVARQYGQ.
Volume 88, Issue 5, Pages (March 1997)

Volume 88, Issue 5, Pages (March 1997)
GC TFH cells exhibit HIV antigen–driven clonal expansion and selection

GC TFH cells exhibit HIV antigen–driven clonal expansion and selection
by Nancy D. Borson, Martha Q. Lacy, and Peter J. Wettstein

by Nancy D. Borson, Martha Q. Lacy, and Peter J. Wettstein
by David W. Bahler, John A. Miklos, and Steven H. Swerdlow

by David W. Bahler, John A. Miklos, and Steven H. Swerdlow
Nienke van der Stoep, James R Gorman, Frederick W Alt  Immunity 

Nienke van der Stoep, James R Gorman, Frederick W Alt  Immunity 
by Takashi Kasukabe, Junko Okabe-Kado, and Yoshio Honma

by Takashi Kasukabe, Junko Okabe-Kado, and Yoshio Honma
Volume 133, Issue 1, Pages (July 2007)

Volume 133, Issue 1, Pages (July 2007)
Characterizing Class I WW domains defines key specificity determinants and generates mutant domains with novel specificities  Jeremy Kasanov, Gregorio.

Characterizing Class I WW domains defines key specificity determinants and generates mutant domains with novel specificities  Jeremy Kasanov, Gregorio.
Tiago R. Matos, Menno A. de Rie, Marcel B.M. Teunissen 

Tiago R. Matos, Menno A. de Rie, Marcel B.M. Teunissen 
by Christian H. Ottensmeier, and Freda K. Stevenson

by Christian H. Ottensmeier, and Freda K. Stevenson
IgA and IgM VH repertoires in human colon: Evidence for clonally expanded B cells that are widely disseminated  Wolfgang Holtmeier, Andreas Hennemann,

IgA and IgM VH repertoires in human colon: Evidence for clonally expanded B cells that are widely disseminated  Wolfgang Holtmeier, Andreas Hennemann,
Demonstration That Mast Cells, T Cells, and B Cells Bearing the Activating Kit Mutation D816V Occur in Clusters within the Marrow of Patients with Mastocytosis 

Demonstration That Mast Cells, T Cells, and B Cells Bearing the Activating Kit Mutation D816V Occur in Clusters within the Marrow of Patients with Mastocytosis 
Characterizing Class I WW domains defines key specificity determinants and generates mutant domains with novel specificities  Jeremy Kasanov, Gregorio.

Characterizing Class I WW domains defines key specificity determinants and generates mutant domains with novel specificities  Jeremy Kasanov, Gregorio.
Deficiency of somatic hypermutation of the antibody light chain is associated with increased frequency of severe respiratory tract infection in common.

Deficiency of somatic hypermutation of the antibody light chain is associated with increased frequency of severe respiratory tract infection in common.

Similar presentations

Ads by Google