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CYP19 gene: a genetic modifier of polycystic ovary syndrome phenotype

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Presentation on theme: "CYP19 gene: a genetic modifier of polycystic ovary syndrome phenotype"— Presentation transcript:

1 CYP19 gene: a genetic modifier of polycystic ovary syndrome phenotype
Nectaria Xita, M.D., Ph.D., Leandros Lazaros, Ph.D., Ioannis Georgiou, Ph.D., Agathocles Tsatsoulis, M.D., Ph.D.  Fertility and Sterility  Volume 94, Issue 1, Pages (June 2010) DOI: /j.fertnstert Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Difference of genotype distribution between patients grouped in quartiles according to total T levels and controls. SS = homozygous for short CYP19(TTTA)n alleles (nine or fewer repeats); SL = heterozygous for short CYP19(TTTA)n alleles; LL = homozygous for long CYP19(TTTA)n alleles (more than nine repeats). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Difference in T/E2 ratio between patients being homozygous (SS) for short CYP19(TTTA)n alleles (nine or fewer repeats) and patients being either heterozygous (SL) or homozygous (LL) for long CYP19(TTTA)n alleles (more than nine repeats). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions


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