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Identification of Desmoglein as a Cadherin and Analysis of Desmoglein Domain Structure
Ken Ishii Journal of Investigative Dermatology Volume 127, Pages E6-E7 (January 2007) DOI: /sj.skinbio Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions
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Figure 1 Structure of desmosomal cadherins (desmoglein and the two splice forms of desmocollin) and the classical cadherin E-cadherin. EC1–EC4, four extracellular cadherin-typical repeats; EA, extracellular anchor domain; TM, transmembrane domain; IA, intracellular anchor domain; ICS, intracellular cadherinspecific domain. Desmoglein contains an additional intracellular domain: IPL, proline-rich linker domain; RUD, repeating unit domain; DTD, desmoglein-specific terminal domain. (Adapted from Amagai, 1996, with permission from Elsevier.) Journal of Investigative Dermatology , E6-E7DOI: ( /sj.skinbio ) Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions
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