1. Oral phenytoin protects against experimental cyclophosphamide-chemotherapy induced hair loss 
A.Y Onaolapo, A.A. Adebayo, O.J Onaolapo 
Pathophysiology 
Volume 25, Issue 1, Pages (March 2018)
DOI: /j.pathophys
Copyright © 2017 Elsevier B.V. Terms and Conditions

2. Fig. 1
Effect of phenytoin on percentage weight change. Values are means±S.E.M. (*p<0.05 significantly different from VEH, #p<0.05 significantly different from CYP, &p<0.005 significantly different from Phenytoin, VEH: vehicle, CYP: cyclophosphamide, PHE 50: phenytoin at 50mg/kg, PHE 100: phenytoin at 100mg/kg, number of animals per group-6.
Pathophysiology  , 31-39DOI: ( /j.pathophys )
Copyright © 2017 Elsevier B.V. Terms and Conditions

3. Fig. 2
Photodocumentation of the effect of phenytoin with or without chemotherapy-induced alopecia in rats. 2A –vehicle, 2B –Phenytoin at 50mg/kg, 2C-Phenytoin at 100mg/kg, 2D- cyclophosphamide control, 2E-cyclophosphamide and phenytoin at 50mg/kg, 2F- cyclophosphamide and phenytoin at 100mg/kg. Photographs were taken on days 9, 23 and 37 respectively, number of animals per group-6.
Pathophysiology  , 31-39DOI: ( /j.pathophys )
Copyright © 2017 Elsevier B.V. Terms and Conditions

4. Fig. 3
Photomicrographs of representative hair strands from all groups. 3A –vehicle, 3B −Phenytoin at 50mg/kg, 3C-Phenytoin at 100mg/kg, 3D- cyclophosphamide control, 3E-cyclophosphamide and phenytoin at 50mg/kg, 3F- cyclophosphamide and phenytoin at 100mg/kg,C: cortex, M: medulla, number of animals per group-6.
Pathophysiology  , 31-39DOI: ( /j.pathophys )
Copyright © 2017 Elsevier B.V. Terms and Conditions

5. Fig. 4
Effect of phenytoin on colour intensity of hair strand. Values are means±S.E.M. (*p<0.05 significantly different from VEH, #p<0.05 significantly different from CYP, &p<0.005 significantly different from PHE, VEH: vehicle, CYP: cyclophosphamide, PHE 50: phenytoin at 50mg/kg, PHE 100: phenytoin at 100mg/kg, number of animals per group-6.
Pathophysiology  , 31-39DOI: ( /j.pathophys )
Copyright © 2017 Elsevier B.V. Terms and Conditions

6. Fig. 5
Effect of phenytoin on mean width of cortex (upper panel) and mean width of medulla (lower panel) of hair strand. Values are means±S.E.M. (*p<0.05 significantly different from VEH, #p<0.05 significantly different from CYP, &p<0.005 significantly different from PHE, VEH: vehicle, CYP: cyclophosphamide, PHE 50: phenytoin at 50mg/kg, PHE 100: phenytoin at 100mg/kg, number of animals per group-6.
Pathophysiology  , 31-39DOI: ( /j.pathophys )
Copyright © 2017 Elsevier B.V. Terms and Conditions

7. Fig. 6
Photomicrographs of representative skin samples from all groups showing hair follicle, hair bulb, hair shaft, and external root sheath. dg hair: degenerating hair follicle. 6A –vehicle, 6B –Phenytoin at 50mg/kg, 6C-Phenytoin at 100mg/kg, 6D- cyclophosphamide control, 6E-cyclophosphamide and phenytoin at 50mg/kg, 6F- cyclophosphamide and phenytoin at 100mg/kg, number of animals per group-6.
Pathophysiology  , 31-39DOI: ( /j.pathophys )
Copyright © 2017 Elsevier B.V. Terms and Conditions