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Decreased proteoglycan degradation in IL-1β-treated cartilage co-cultured with TIMP-3- transduced cells  J. Mason, A. Donahue, A. Yoskowitz, D. Richardson 

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1 Decreased proteoglycan degradation in IL-1β-treated cartilage co-cultured with TIMP-3- transduced cells  J. Mason, A. Donahue, A. Yoskowitz, D. Richardson  Osteoarthritis and Cartilage  Volume 21, Pages S207-S208 (April 2013) DOI: /j.joca Copyright © Terms and Conditions

2 Figure 1 Glycosaminoglycan changes in articular cartilage before and after in vitro-culture. IL-1β significantly decreased the amount of GAG contained in cartilage post-culture. Error bars represent SE. Osteoarthritis and Cartilage  , S207-S208DOI: ( /j.joca ) Copyright © Terms and Conditions

3 Figure 2 Glycosaminoglycan changes in articular cartilage exposed to TIMP-3. Co-culture with TIMP-3-transduced cells significantly increased the amount of GAG contained in IL-1β-cultured cartilage. Error bars represent SE. Osteoarthritis and Cartilage  , S207-S208DOI: ( /j.joca ) Copyright © Terms and Conditions

4 Figure 3 Aggrecan changes in articular cartilage exposed to TIMP-3. Co-culture with TIMP-3-transduced cells significantly decreased the amount of the degraded -aggrecan fragment, ARGSVIL released into the media of IL-1β-cultured cartilage. Error bars represent SE. Osteoarthritis and Cartilage  , S207-S208DOI: ( /j.joca ) Copyright © Terms and Conditions


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