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Donor KIR Genes 2DL5A, 2DS1 and 3DS1 Are Associated with a Reduced Rate of Leukemia Relapse After HLA-Identical Sibling Stem Cell Transplantation for.

Published bySolomon Terry Modified over 5 years ago

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Presentation on theme: "Donor KIR Genes 2DL5A, 2DS1 and 3DS1 Are Associated with a Reduced Rate of Leukemia Relapse After HLA-Identical Sibling Stem Cell Transplantation for."— Presentation transcript:

1 Donor KIR Genes 2DL5A, 2DS1 and 3DS1 Are Associated with a Reduced Rate of Leukemia Relapse After HLA-Identical Sibling Stem Cell Transplantation for Acute Myeloid Leukemia but Not Other Hematologic Malignancies  Kate Stringaris, Sharon Adams, Marcela Uribe, Rhoda Eniafe, Colin O. Wu, Bipin N. Savani, A. John Barrett  Biology of Blood and Marrow Transplantation  Volume 16, Issue 9, Pages (September 2010) DOI: /j.bbmt Copyright © Terms and Conditions

2 Figure 1 Factors affecting SCT outcome in multivariate analysis of 261 patients. (A) Lymphocyte count at day 30 posttransplant and TRM; (B) donor KIR genotype and relapse. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © Terms and Conditions

3 Figure 2 Effect of donor KIR genes on relapse in AML patients (n = 68). (A) Stratified by donor KIR genes; (B) stratified by donor KIR and patient risk group. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © Terms and Conditions

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