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Clinical Microbiology and Infection

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Presentation on theme: "Clinical Microbiology and Infection"— Presentation transcript:

1 Clinical Microbiology and Infection
Probiotics and the immunological response to infant vaccinations; a double-blind randomized controlled trial  C. Adler Sørensen, E. Fuglsang, C. Sværke Jørgensen, R. Pilmann Laursen, A. Larnkjær, C. Mølgaard, C. Ritz, K.F. Michaelsen, K. Angeliki Krogfelt, H. Frøkiær  Clinical Microbiology and Infection  DOI: /j.cmi Copyright © 2018 The Authors Terms and Conditions

2 Fig. 1 Flowchart of participants and number of blood samples analysed.
Clinical Microbiology and Infection DOI: ( /j.cmi ) Copyright © 2018 The Authors Terms and Conditions

3 Fig. S1 Antibody response towards 13-valent pneumococcal conjugate vaccine (PCV13) or Bordetella pertussis toxin (PT) at baseline to end of study (PCV13: placebo, n = 86; probiotics, n = 103. PT: placebo, n = 55; probiotics, n = 41). Clinical Microbiology and Infection DOI: ( /j.cmi ) Copyright © 2018 The Authors Terms and Conditions

4 Fig. S2 Impact of time (measured in days) since last vaccination on antibody responses in all children included. Clinical Microbiology and Infection DOI: ( /j.cmi ) Copyright © 2018 The Authors Terms and Conditions

5 Fig. S3 Cytokine concentrations upon ex vivo lipopolysaccharide (LPS) stimulation of whole blood at baseline to the end of study (interleukin: placebo, n = 67; probiotics, n = 51. interferon-γ: placebo, n = 81; probiotics, n = 103). Clinical Microbiology and Infection DOI: ( /j.cmi ) Copyright © 2018 The Authors Terms and Conditions


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