1. The role of fourth-generation cephalosporins in the treatment of infections caused by penicillin-resistant streptococci 
Keith Klugman, Fred Goldstein, Shigeru Kohno, Fernando Baquero 
Clinical Microbiology and Infection 
Volume 3, Pages S48-S60 (April 1997)
DOI: /j tb00646.x
Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions

2. Figure 1
World-wide frequency of isolation of penicillin-resistant pneumococci (MIC > 0.12 mg/L, intermediate and high-level penicillin-resistant strains).
Clinical Microbiology and Infection 1997 3, S48-S60DOI: ( /j tb00646.x)
Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions

3. Figure 2
Effect of increasing the MIC values of penicillin on the 50% effective dose (ED50) in a S. pneumoniae peritonitis mouse model following penicillin treatment. From Knudsen et al. 50. With permission of Am Soc Microbiol J Div.
Clinical Microbiology and Infection 1997 3, S48-S60DOI: ( /j tb00646.x)
Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions