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Cystic Fibrosis Patients Benefit from Mini Guts

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Presentation on theme: "Cystic Fibrosis Patients Benefit from Mini Guts"— Presentation transcript:

1 Cystic Fibrosis Patients Benefit from Mini Guts
Angela Saini  Cell Stem Cell  Volume 19, Issue 4, Pages (October 2016) DOI: /j.stem Copyright © Terms and Conditions

2 19- year-old Fabian, who lives in the Netherlands, has been the first Cystic Fribrosis patient to be helped using intestinal organoid technology. The photo was taken in November 2015, after his treatment with Kalydeco had begun. Image courtesy of the patient. Cell Stem Cell  , DOI: ( /j.stem ) Copyright © Terms and Conditions

3 Organoids from a healthy individual (WT) and a cystic fibrosis patient (F508del). The WT organoids have properly functioning ion channels, which allow them to swell. With appropriate drugs, the organoid of a cytic fibrosis patient will see similar swelling. Image courtesy of Jeffrey Beekman and Kors van der Ent. Cell Stem Cell  , DOI: ( /j.stem ) Copyright © Terms and Conditions


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