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Pharmacotherapy for Diabetic Coronary Disease:

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Presentation on theme: "Pharmacotherapy for Diabetic Coronary Disease:"— Presentation transcript:

1 Pharmacotherapy for Diabetic Coronary Disease:

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5 Trials Targeting Lower HbA1c Levels

6 VADT: CV Risk Factor Control

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8 Look AHEAD: Lifestyle Intervention Did Not Reduce Hard End Points

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12 UKPDS: Metformin and Outcomes in New T2D at 36 Months

13 ADVANCE: Reducing HbA1c Lowers Microvascular Events

14 VADT: Intensive Treatment Reduces CVD Events in Cases With Lower Calcified Coronary Atherosclerosis

15 Look AHEAD: Earlier Intervention Beneficial?

16 SAVOR-TIMI 53 and EXAMINE: Conclusions

17 Changes in Microalbuminuria

18 Baseline NT-proBNP and Hospitalization for Heart Failure

19 SAVOR-TIMI 53: Hypoglycemia

20 SAVOR-TIMI 53: Hypoglycemia by Baseline Medication and HbA1c

21 ORIGIN: Severe Hypoglycemia and Outcome

22 ACCORD: Hypoglycemia and Mortality Worse in Standard Group

23 ESC/EASD Guidelines: Glycemic Control in Diabetes

24 ESC/EASD Guidelines: Glycemic Control in Diabetes

25 In Summary

26 Abbreviations

27 Abbreviations (cont)

28 Abbreviations (cont)

29 References

30 References (cont)

31 References (cont)

32 References (cont)

33 References (cont)

34 References (cont)


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