1. JPIAMR Joint Research Calls – Update and Future Calls
Management Board Meeting
24th October, 2018
Laura Plant
JPIAMR Secretariat

2. Overview of Calls ERA-net cofund “Emerging Pollutants”
ERA-net cofund “JPInterventAMR”

3. JPInterventAMR ERA-net Cofund Continuation of JP-EC-AMR
SRIA primary pillar: Interventions
SRIA sub-pillars: Surveillance, Transmission and Environment
ERA-net within Societal Challenge 1:
Health, demographic change and wellbeing

4. JPI-EC-AMR 2015-2019 19 partners from 16 countries + Canada
The aim of this programme is to unravel the complex dynamics of selection and transmission of antimicrobial resistance (AMR) according to the One Health concept. A multidisciplinary approach is necessary to identify and characterise the determinants that contribute to the spread of resistance at genetic, bacterial, animal, human, societal, and environmental levels, in order to provide scientific knowledge to design and evaluate cost-effective strategies that can decrease transmission of AMR in society.

5. JPI-EC-AMR 2015-2019 JPIAMR has used the ERA-net to fund:
4 research calls
Transmission and Selection of Resistance in Humans, Animals, and the Environment
Comparison of prevention, control and intervention strategies for AMR infections through multidisciplinary studies, including One Health approaches
Therapeutics: New targets, compounds and tools
2019 Call: Diagnostics and Surveillance
3 network calls
Transnational working groups
Working to improve surveillance
Building the foundations of the JPIAMR-VRI

6. JPInterventAMR
One Health interventions to prevent or reduce the development and transmission of antimicrobial resistance (AMR)
General focus of the call: Interventions and Transmission
Other JPIAMR key areas:
One Health
LMIC
Surveillance
Environment

7. Two placeholders for ERA-net cofund are under discussion for WP2020 in program committee for health
Three suggestions on ERA-net cofund have very similar support from the member states at the moment
The possibility for three ERA-nets is very uncertain. Therefore it is highly important for countries to express their priority to the commission if that has not been done yet (deadline Nov 5)

8. JPInterventAMR Focal area 1
Understanding the impact of interventions on the transmission of AMR in, and between, different reservoirs.
What are the determinants and risks contributing to the spread of resistance in and between different One Health reservoirs, and what are their transmission dynamics?
How can interventions impact the emergence and spread of AMR from One Health reservoirs?
How can surveillance of AMR contribute to limiting transmission between One Health reservoirs?

9. JPInterventAMR Focal area 2
Designing and evaluating interventions to control the selection and transmission of AMR in different One Health reservoirs.
What are the critical control points at which interventions could substantially affect the spread of resistance?
What behavioural strategies can be implemented to improve antibiotic stewardship and reduce unnecessary use in human, animal, hospital, and community settings?
How can technical interventions for antibiotic stewardship result in education and empowerment to reduce AMR in clinical care?
What are the most cost-effective interventions for preventing antibiotic resistance transmission between bacterial species, humans, animals, and across regional, national and international borders?

10. JPInterventAMR Additional activities
One additional call: focus on low and lower middle income countries addressing specific challenges relating to stewardship - access, implementation research and knowledge
Further additional calls:
Large-scale prevention trials that cannot be supported by single countries.
What is the optimal way to design, analyse and report the results of stewardship and infection control intervention trials?

11. JPInterventAMR Impact
Assessment of the usefulness and cost-effectiveness of new One Health interventions
Implementation of novel strategies and methodologies, and harmonisation of actions across JPIAMR countries
Prevention of antibiotic-resistant infections
Improved quality of human and animal health
Decreased levels of AMR in the environment

12. JPInterventAMR
If your agency wishes to join the JPInterventAMR call contact Maria Starborg at the JPIAMR Secretariat:

13. Aquatic Pollutants 2019: Emerging pollutants and pathogens
ERA-net Cofund
SRIA primary pillar: Environment
SRIA sub-pillars: Transmission and Interventions
ERA-net within Societal Challenge 5:
Climate action, environment, resource efficiency and raw materials

14. Keywords from JPIAMR supported projects related to Water
General Overview of JPIAMR funded projects and networks
Total investment of ~66 M €
8 Joint transnational calls
70 projects supported
Keywords from JPIAMR supported projects related to Water
Overview of JPIAMR funded projects in Water
14 projects on Environment
Out of which 4 are related to water
Projects on Environment
~19 M€ invested in Environment projects
Of which ~7.5 M€ invested in water related projects
Investments

15. Aquatic Pollutants 2019 Emerging pollutants and pathogens
Germany is coordinating the ERA-net
Project Management Jülich (PTJ)
Estimated Contributions:
EC 5M €
National 22.5M €
To date:
>20 funding agencies from >18 countries have declared interest to join
Deadline for applications Feb 19th 2019

16. Aquatic Pollutants 2019 Emerging pollutants and pathogens
Deadline for applications Feb 19th 2019
Cofunded call: 2020, 2nd mandatory call 2021

17. Aquatic Pollutants 2019 Emerging pollutants and pathogens
Pesticides
Biozides, including industrial chemicals and complexing agents
Antibiotics and antibiotic-resistant bacteria
Pharmaceuticals
Personal care products
Microplastics
Synthetic hormones
Radio-opaque substances …

18. Aquatic Pollutants 2019 Emerging pollutants and pathogens
General focus of the call: risk management of emerging pollutants and pathogens in aquatic ecosystems
Three main areas have been proposed:
Environmental behaviour of emerging pollutants and pathogens, including antimicrobial resistant bacteria, in aquatic environments
Risk assessment and Management of emerging pollutants and pathogens, including antimicrobial resistant bacteria, from aquatic ecosystems
Strategies to reduce pollutants and pathogens, including antimicrobial resistant bacteria

19. Aquatic Pollutants 2019 Emerging pollutants and pathogens
Expected timeline
NOV 22, 2018: 2nd funders meeting
JAN 10, 2019: 3rd Funders Meeting.
FEB 15, 2019: Pre-submission of proposal
FEB 19, 2019: Deadline of the proposal

20. Aquatic Pollutants 2019 Emerging pollutants and pathogens
If your agency wishes to join the Aquatic Pollutants 2019 consortium contact Maria Starborg at the JPIAMR Secretariat: