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Rare and Deadly The American Journal of Medicine

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Presentation on theme: "Rare and Deadly The American Journal of Medicine"— Presentation transcript:

1 Rare and Deadly The American Journal of Medicine
Jesse J. Keller, BS, Zarry Tavakkol, MD, Andrea Kalus, MD  The American Journal of Medicine  Volume 124, Issue 1, Pages (January 2011) DOI: /j.amjmed Copyright © 2011 Elsevier Inc. Terms and Conditions

2 Figure 1 The patient had a few scattered discrete vesicles in a predominantly acral distribution. A, The patient's dorsal hand served as 1 site. B, The patient's ankle also was affected. The American Journal of Medicine  , 32-34DOI: ( /j.amjmed ) Copyright © 2011 Elsevier Inc. Terms and Conditions

3 Figure 2 Two patients were treated for fulminant hepatitis associated with herpes simplex virus at our institution. Composite data are shown here. IV, intravenous; PO, oral; d, days. The American Journal of Medicine  , 32-34DOI: ( /j.amjmed ) Copyright © 2011 Elsevier Inc. Terms and Conditions

4 Figure 3 These microscopic findings come from a similar case (patient 2). A, A hematoxylin and eosin stain of a skin biopsy demonstrated an intraepidermal vesicle and characteristic viral cytopathic changes in adjacent keratinocytes (arrow). B, A hematoxylin and eosin stain of a liver biopsy demonstrated an area of necrosis with minimal surrounding inflammation (arrow). C, Immunohistochemical staining for herpes simplex virus confirmed the presence of viral antigens in the liver specimen. The American Journal of Medicine  , 32-34DOI: ( /j.amjmed ) Copyright © 2011 Elsevier Inc. Terms and Conditions


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