1. Expert Perspectives on NIPT

2. Definition of Aneuploidy

3. Cell-Free DNA

4. Mosaicism

5. Risk of DS or Any Chromosomal Abnormality

6. Value of NIPT

7. Alternatives to NIPT

8. Detection Rates of DS Using Various Screening Modalities

9. False Positive Rates Using Various Screening Modalities

10. Causes of False Positive Rates in NIPT

11. Clinical Utility of NIPT PPV

12. NIPT Performance Characteristics PPV

13. Pretest Counseling General Overview

14. Pretest Counseling NIPT

15. Causes of No-Call Results in NIPT

16. Causes of Low Fetal Fraction

17. Managing Patients With Low Fetal Fraction

18. Incidence of Chromosomal Abnormalities

19. NIPT Performance Characteristics

20. Other Information Provided by NIPT

21. Conditions Not Detected in NIPT

22. Value of Offering NIPT Patients an Early Ultrasound at 12 to 14 Weeks

23. Conclusions

24. Abbreviations