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The pathogenesis of ovarian hyperstimulation syndrome: in vivo studies investigating the role of interleukin-1β, interleukin-6, and vascular endothelial.

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Presentation on theme: "The pathogenesis of ovarian hyperstimulation syndrome: in vivo studies investigating the role of interleukin-1β, interleukin-6, and vascular endothelial."— Presentation transcript:

1 The pathogenesis of ovarian hyperstimulation syndrome: in vivo studies investigating the role of interleukin-1β, interleukin-6, and vascular endothelial growth factor  Antonio Pellicer, M.D., Carmela Albert, Ph.D., Amparo Mercader, Ph.D., Fernando Bonilla-Musoles, M.D., José Remohí, M.D., Carlos Simón, M.D.  Fertility and Sterility  Volume 71, Issue 3, Pages (March 1999) DOI: /S (98)

2 FIGURE 1 Serum and follicular fluid levels of interleukin (IL)-1β (▧), IL-6 (▩), and vascular endothelial growth factor (VEGF, □) according to clinical outcome. ∗ versus †P<.05 (determined by Kruskal-Wallis test). Fertility and Sterility  , DOI: ( /S (98) )

3 FIGURE 2 Basal serum and follicular fluid levels of interleukin (IL)-1β (▧), IL-6 (▩), and vascular endothelial growth factor (VEGF, □) in natural cycles. PCOS = polycystic ovary syndrome. Fertility and Sterility  , DOI: ( /S (98) )

4 FIGURE 3 Serum (top panel) and follicular fluid (bottom panel) concentrations of E2 (□), interleukin (IL)-1β (○), IL-6 (□), and vascular endothelial growth factor (VEGF, •) relative to basal values. EFP = early follicular phase; MFP = midfollicular phase; LFP = late follicular phase; ELP = early luteal phase. Fertility and Sterility  , DOI: ( /S (98) )


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