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Primary cutaneous Epstein-Barr virus–related lymphoproliferative disorders in 4 immunosuppressed children  Nadège Wallet-Faber, MD, Christine Bodemer,

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Presentation on theme: "Primary cutaneous Epstein-Barr virus–related lymphoproliferative disorders in 4 immunosuppressed children  Nadège Wallet-Faber, MD, Christine Bodemer,"— Presentation transcript:

1 Primary cutaneous Epstein-Barr virus–related lymphoproliferative disorders in 4 immunosuppressed children  Nadège Wallet-Faber, MD, Christine Bodemer, MD, Stéphane Blanche, MD, Eric Delabesse, MD, Catherine Eschard, MD, Nicole Brousse, MD, Sylvie Fraitag, MD  Journal of the American Academy of Dermatology  Volume 58, Issue 1, Pages (January 2008) DOI: /j.jaad Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Case 1. A, Infiltration of whole dermis by lymphocytes with large nuclei and ample cytoplasms. B, Intense staining for CD3, indicative of T-cell lineage. C, Cells containing Epstein-Barr virus–encoded small nuclear RNA demonstrated by in situ hybridization. D, Kaposiform lesion on left leg. (A to C, Hematoxylin-eosin stain; original magnifications: A and C, ×100; B, ×25.) Journal of the American Academy of Dermatology  , 74-80DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Case 2. Dense nodular and interstitial lymphoid infiltrate extending through whole dermis. (Hematoxylin-eosin stain; original magnification: ×100.) Journal of the American Academy of Dermatology  , 74-80DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

4 Fig 3 Case 3. Dense large cell lymphoid infiltrate of subcutaneous tissue. (Hematoxylin-eosin stain; original magnification: ×200.) Journal of the American Academy of Dermatology  , 74-80DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

5 Fig 4 Case 4. A, Ulceronecrotic vulvar lesion. B, Large lymphocytes with abundant cytoplasms and pleomorphic nuclei, and scanty reactive infiltrate of small lymphocytes. (Hematoxylin-eosin stain; original magnification: ×100.) Journal of the American Academy of Dermatology  , 74-80DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

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