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ASGE Technology Committee systematic review and meta-analysis assessing the ASGE Preservation and Incorporation of Valuable Endoscopic Innovations thresholds.

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Presentation on theme: "ASGE Technology Committee systematic review and meta-analysis assessing the ASGE Preservation and Incorporation of Valuable Endoscopic Innovations thresholds."— Presentation transcript:

1 ASGE Technology Committee systematic review and meta-analysis assessing the ASGE Preservation and Incorporation of Valuable Endoscopic Innovations thresholds for adopting real-time imaging–assisted endoscopic targeted biopsy during endoscopic surveillance of Barrett’s esophagus  Nirav Thosani, MD, Barham K. Abu Dayyeh, MD, MPH, Prateek Sharma, MD, FASGE, Harry R. Aslanian, MD, FASGE, Brintha K. Enestvedt, MD, MBA, Sri Komanduri, MD, FASGE, Michael Manfredi, MD, Udayakumar Navaneethan, MD, John T. Maple, DO, FASGE, Rahul Pannala, MD, MPH, FASGE, Mansour A. Parsi, MD, FASGE, Zachary L. Smith, DO, Shelby A. Sullivan, MD, Subhas Banerjee, MD, FASGE  Gastrointestinal Endoscopy  Volume 83, Issue 4, Pages e7 (April 2016) DOI: /j.gie Copyright © Terms and Conditions

2 Figure 1 Flow diagram depicting included studies selection for the meta-analysis. CINAHL, Cumulative Index to Nursing and Allied Health Literature; BE, Barrett's esophagus; CLE, confocal laser endomicroscopy; NBI, narrow-band imaging; eCLE, endoscope-based CLE; pCLE, probe-based CLE; PIVI, ASGE Preservation and Incorporation of Valuable Endoscopic Innovations. Gastrointestinal Endoscopy  , e7DOI: ( /j.gie ) Copyright © Terms and Conditions

3 Figure 2 A, Forest plot of studies evaluating sensitivity. B, Forest plot of studies evaluating negative predictive value. C, Forest plot of studies evaluating specificity of chromoendoscopy-guided targeted biopsy against current standard biopsy protocol during surveillance of nondysplastic Barrett’s esophagus. NPV, negative predictive value. Gastrointestinal Endoscopy  , e7DOI: ( /j.gie ) Copyright © Terms and Conditions

4 Figure 2 A, Forest plot of studies evaluating sensitivity. B, Forest plot of studies evaluating negative predictive value. C, Forest plot of studies evaluating specificity of chromoendoscopy-guided targeted biopsy against current standard biopsy protocol during surveillance of nondysplastic Barrett’s esophagus. NPV, negative predictive value. Gastrointestinal Endoscopy  , e7DOI: ( /j.gie ) Copyright © Terms and Conditions

5 Figure 3 A, Forest plot of studies evaluating sensitivity. B, Forest plot of studies evaluating negative predictive value. C, Forest plot of studies evaluating specificity of narrow-band imaging–guided targeted biopsy against current standard biopsy protocol during surveillance of nondysplastic Barrett’s esophagus. NBI, narrow-band imaging; NPV, negative predictive value. Gastrointestinal Endoscopy  , e7DOI: ( /j.gie ) Copyright © Terms and Conditions

6 Figure 3 A, Forest plot of studies evaluating sensitivity. B, Forest plot of studies evaluating negative predictive value. C, Forest plot of studies evaluating specificity of narrow-band imaging–guided targeted biopsy against current standard biopsy protocol during surveillance of nondysplastic Barrett’s esophagus. NBI, narrow-band imaging; NPV, negative predictive value. Gastrointestinal Endoscopy  , e7DOI: ( /j.gie ) Copyright © Terms and Conditions

7 Figure 4 A, Forest plot of studies evaluating sensitivity. B, Forest plot of studies evaluating negative predictive value. C, Specificity of confocal laser endomicroscopy–guided targeted biopsy against current standard biopsy protocol during surveillance of nondysplastic Barrett’s esophagus. CLE, confocal laser endomicroscopy; eCLE, endoscope-based confocal laser endomicroscopy; pCLE, probe-based confocal laser endomicroscopy; NPV, negative predictive value. Gastrointestinal Endoscopy  , e7DOI: ( /j.gie ) Copyright © Terms and Conditions

8 Figure 4 A, Forest plot of studies evaluating sensitivity. B, Forest plot of studies evaluating negative predictive value. C, Specificity of confocal laser endomicroscopy–guided targeted biopsy against current standard biopsy protocol during surveillance of nondysplastic Barrett’s esophagus. CLE, confocal laser endomicroscopy; eCLE, endoscope-based confocal laser endomicroscopy; pCLE, probe-based confocal laser endomicroscopy; NPV, negative predictive value. Gastrointestinal Endoscopy  , e7DOI: ( /j.gie ) Copyright © Terms and Conditions

9 Supplemental Figure 1 Publication bias funnel plot for chromoendoscopy (A), narrow-band imaging (B), autofluorescence imaging with NBA (C), and confocal laser endomicroscopy (D). Gastrointestinal Endoscopy  , e7DOI: ( /j.gie ) Copyright © Terms and Conditions

10 Supplemental Figure 1 Publication bias funnel plot for chromoendoscopy (A), narrow-band imaging (B), autofluorescence imaging with NBA (C), and confocal laser endomicroscopy (D). Gastrointestinal Endoscopy  , e7DOI: ( /j.gie ) Copyright © Terms and Conditions


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