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Safety and efficacy of the prostaglandin D2 receptor antagonist AMG 853 in asthmatic patients  William W. Busse, MD, Sally E. Wenzel, MD, Eli O. Meltzer,

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Presentation on theme: "Safety and efficacy of the prostaglandin D2 receptor antagonist AMG 853 in asthmatic patients  William W. Busse, MD, Sally E. Wenzel, MD, Eli O. Meltzer,"— Presentation transcript:

1 Safety and efficacy of the prostaglandin D2 receptor antagonist AMG 853 in asthmatic patients 
William W. Busse, MD, Sally E. Wenzel, MD, Eli O. Meltzer, MD, Edward M. Kerwin, MD, Mark C. Liu, MD, Nan Zhang, PhD, Yun Chon, PhD, Alison L. Budelsky, PhD, Joseph Lin, MD, Shao-Lee Lin, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 131, Issue 2, Pages (February 2013) DOI: /j.jaci Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Change from baseline in total ACQ score for patients receiving placebo, 5 mg of AMG 853 BID, 25 mg of AMG 853 BID, 100 mg of AMG 853 BID, and 200 mg of AMG 853 QD. BL, Baseline. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Change from baseline in prebronchodilator percent predicted FEV1 for patients receiving placebo, 5 mg of AMG 853 BID, 25 mg of AMG 853 BID, 100 mg of AMG 853 BID, and 200 mg of AMG 853 QD. BL, Baseline. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2012 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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