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Two Fresh Streams to Fill the Liver’s Hepatocyte Pool
Thomas G. Bird, Stuart J. Forbes Cell Stem Cell Volume 17, Issue 4, Pages (October 2015) DOI: /j.stem Copyright © 2015 Elsevier Inc. Terms and Conditions
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Figure 1 Regeneration of the Hepatic Lobule from Both Periportal and Pericentral Sources This diagram depicts the liver lobule from the periportal area, containing Sox9+ HybHPs around the portal vein and biliary tree, to the pericentral area, where Axin2+ hepatocytes surround the central vein. The contribution to hepatocellular regeneration by each population is shown in both homeostasis and injury; dashed arrows represent areas of uncertainty. Cell Stem Cell , DOI: ( /j.stem ) Copyright © 2015 Elsevier Inc. Terms and Conditions
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