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Multiplex Screening for Blood-Borne Viral, Bacterial, and Protozoan Parasites using an OpenArray Platform  Elena Grigorenko, Carolyn Fisher, Sunali Patel,

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Presentation on theme: "Multiplex Screening for Blood-Borne Viral, Bacterial, and Protozoan Parasites using an OpenArray Platform  Elena Grigorenko, Carolyn Fisher, Sunali Patel,"— Presentation transcript:

1 Multiplex Screening for Blood-Borne Viral, Bacterial, and Protozoan Parasites using an OpenArray Platform  Elena Grigorenko, Carolyn Fisher, Sunali Patel, Caren Chancey, Maria Rios, Hira L. Nakhasi, Robert C. Duncan  The Journal of Molecular Diagnostics  Volume 16, Issue 1, Pages (January 2014) DOI: /j.jmoldx Copyright © 2014 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

2 Figure 1 The decision tree for interpretation of BBP OpenArray results. This flow diagram indicates the series of questions that would be asked of each assay result, then the results of each pair of assays that detect a particular pathogen to determine whether the results indicate that pathogen has been detected. The flow initiates at the upper left corner. Ct Con, Ct confidence (a measure of the quality of the amplification curve). Asterisk: One exception to this rule is made for the P. falciparum assays, which have a higher level of specificity; Cq values up to 35 are accepted to indicate the presence of that pathogen. The Journal of Molecular Diagnostics  , DOI: ( /j.jmoldx ) Copyright © 2014 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions


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