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Self-expanding transcatheter aortic valve replacement using alternative access sites in symptomatic patients with severe aortic stenosis deemed extreme.

Published byГашпер Борисављевић Modified over 5 years ago

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Presentation on theme: "Self-expanding transcatheter aortic valve replacement using alternative access sites in symptomatic patients with severe aortic stenosis deemed extreme."— Presentation transcript:

1 Self-expanding transcatheter aortic valve replacement using alternative access sites in symptomatic patients with severe aortic stenosis deemed extreme risk of surgery  Michael J. Reardon, MD, David H. Adams, MD, Joseph S. Coselli, MD, G. Michael Deeb, MD, Neal S. Kleiman, MD, Stan Chetcuti, MD, Steven J. Yakubov, MD, David Heimansohn, MD, James Hermiller, MD, G. Chad Hughes, MD, J. Kevin Harrison, MD, Kamal Khabbaz, MD, Peter Tadros, MD, George L. Zorn, MD, William Merhi, MD, John Heiser, MD, George Petrossian, MD, Newell Robinson, MD, Brijeshwar Maini, MD, Mubashir Mumtaz, MD, Joon Sup Lee, MD, Thomas G. Gleason, MD, Jon Resar, MD, John Conte, MD, Daniel Watson, MD, Sharla Chenoweth, MS, Jeffrey J. Popma, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 148, Issue 6, Pages e7 (December 2014) DOI: /j.jtcvs Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Study flow. The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Changes in mean aortic valve gradient (blue) and mean effective orifice area (red) during the study period at each follow-up point. The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

4 Figure E1 CoreValve transcatheter heart valve. The self-expanding nitinol frame serves to anchor the transcatheter heart valve at the level of the aortic annulus. The supra-annular trileaflet porcine pericardial valve is hand sewn to the nitinol frame. The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

5 Figure E2 Cumulative event curve for all-cause mortality or major stroke. Event rates were calculated using the Kaplan-Meier method. Brackets indicate 95% confidence intervals. The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

6 Figure E3 New York Heart Association (NYHA) classification during the study period. Symptom status according to New York Heart Association class is shown at baseline and 30 days, 6 months, and 12 months for patients undergoing attempted transcatheter aortic valve replacement. The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

7 Figure E4 Changes in paravalvular regurgitation during the study period. The percentage of patients by degree of paravalvular aortic regurgitation is shown at each follow-up interval. TAVR, Transcatheter aortic valve replacement. The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions

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