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STDs Herpes genitalis & Syphilis
Dominik Kralj Mentor: A. Žmegač Horvat
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Herpes genitalis - ethiology
HSV-2 virus, herpesviridae family neurotropic, neuroinvasive DNA virus
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Primary infection acquired through sexual contact
presents itself with clusters of genital sores consisting of inflamed papules and vesicles
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Accompanying symptoms:
pain itching burning discharge fever headache myalgia lymphadenitis malaise dysuria cervicitis proctitis reccuring infections often manifest themselves less severely
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Latency
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Treatment 5 x 200mg for 5 days
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Syphilis caused by spirochetal bacterium Treponema pallidum
known throughout history under different names (French disease, great pox, lues, Cupid’s disease) today less prevalent but still poses a problem, especially in underdeveloped countries has three stages
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Primary syphilis usually through direct sexual contact
appearance of a chancre at the point of exposure after three weeks a painless, firm skin ulceration which heals on its own after 4 to 6 weeks sometimes accompanied by lymphadenopathy
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Secondary syphilis 1 to 6 months after primary infection
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Tertiary syphilis appears following a 1atency period which lasts 1 to 10 years characterized by formation of gummas (inflammatory granulomas) other severe manifestations include cardiovascular syphilis, neurosyphilis, neuropathic joint disease
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Diagnostics Treponemal -TPHA -FTA-ABS Nontreponemal -VDRL -RPR
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Therapy Penicilin G 2.4 million IU (intramuscular)
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Thank you for your attention!
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