1. MCB Exam 3 Review
Fall 2018

2. Cytoplasmic streaming
Continuous motion of the cytoplasm typically occurring in large cells
Multicellular organisms (animal, plant, single cell prokaryotes) tend to be limited in size (1-100um) likely reflecting a limit on effective diffusion
Current hypothesis:
Streaming is a form of compensation for larger cell sizes
Molecular motors (myosin-actin) along the cytoskeleton  circulation of cytoplasmic fluid
Enhances nutrient transport, facilitates metabolite interactions, moves organelles e.g. chloroplasts, etc

3. Cells of the Nervous System (Mercer)
Know all the cell types presented in lecture – neurons, glia
What are the different types of cells in each category? What roles do they play?
Understand how signals are transferred across a neuronal synapse
Chemical vs electrical
Know what happens at the neuromuscular junction
Understand the role of neurotransmitters
Examples? What do they do? Excitatory vs inhibitory?

4. Plant Cell Biology (Dixit)
What makes plant cells different from animal cells?
Cell division
Membrane transporters
Organelles
Cytoskeleton
Osmotic regulation/maintenance of cell volume
Modes of intracellular transport

5. ECM and Cell-Matrix Interactions (Miner)
ECM – key proteins, function
Basement membrane – key proteins, function
Role of integrins - How are they activated? What do they bind? Why do we need them?
Collagen vs elastin synthesis – what happens if something goes wrong?
Know the diseases discussed in these lectures
Collagen/elastin = extremely important and ubiquitous structural proteins

6. Prions (True)

7. Good luck!