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Correlation between dysplasia and mutations of six tumor suppressor genes in Barrett’s esophagus  Siva Raja, BS, Sydney D Finkelstein, MD, Fabien K Baksh,

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Presentation on theme: "Correlation between dysplasia and mutations of six tumor suppressor genes in Barrett’s esophagus  Siva Raja, BS, Sydney D Finkelstein, MD, Fabien K Baksh,"— Presentation transcript:

1 Correlation between dysplasia and mutations of six tumor suppressor genes in Barrett’s esophagus 
Siva Raja, BS, Sydney D Finkelstein, MD, Fabien K Baksh, MD, William E Gooding, MS, Patricia A Swalsky, BS, Tony E Godfrey, PhD, Percival O Buenaventura, MD, James D Luketich, MD  The Annals of Thoracic Surgery  Volume 72, Issue 4, Pages (October 2001) DOI: /S (01)

2 Fig 1 (A) Hematoxylin and eosin–stained section of esophagus with microdissection of adenocarcinoma (A), crypt of Barrett’s esophagus (C), and normal skeletal muscle tissue (N). (B) Serial hematoxylin and eosin–stained sections showing crypt microdissection (arrow). The Annals of Thoracic Surgery  , DOI: ( /S (01) )

3 Fig 2 Typical autoradiograph showing the loss of heterozygosity (LOH) in a pentanucleotide polymorphism from a tumor sample (right) relative to a normal sample (left) from the same patient. The Annals of Thoracic Surgery  , DOI: ( /S (01) )


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