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T Regulatory Cell Kinetics Are Altered in a Target Organ of Chronic GVHD, Resulting in a Low T Regulatory to T Effector Memory Cell Ratio  Nataliya Prokopenko.

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Presentation on theme: "T Regulatory Cell Kinetics Are Altered in a Target Organ of Chronic GVHD, Resulting in a Low T Regulatory to T Effector Memory Cell Ratio  Nataliya Prokopenko."— Presentation transcript:

1 T Regulatory Cell Kinetics Are Altered in a Target Organ of Chronic GVHD, Resulting in a Low T Regulatory to T Effector Memory Cell Ratio  Nataliya Prokopenko Buxbaum, MD, Donald Eugene Farthing, PhD, Andrea Carpenter Boehrer, PhD, Veena Kapoor, BS, Ehydel Castro, MD, Nicolas Jean Bouladoux, PhD, Gregory Swan, BS, William Telford, PhD, Michael Eckhaus, DVM, Yasmine Belkaid, PhD, Remy Bosselut, MD, PhD, Ronald Gress, MD  Biology of Blood and Marrow Transplantation  Volume 21, Issue 2, Pages S327-S328 (February 2015) DOI: /j.bbmt Copyright © Terms and Conditions

2 Figure 1 Total number of CD4+ Treg and Tem cells in the syngeneic vs. allogeneic recipients. Shown are total number of CD4+ Treg and Tem cells in the graft (day 0), and at subsequent time points following AHSCT for syngeneic (syn) recipients, identical host recipient pairs; and allogeneic (allo) recipients, with minor antigen mismatch between host and donor with resultant cGVHD induction. Day+14 is a time point early post AHSCT, while day +28 represents well-established cGVHD. Biology of Blood and Marrow Transplantation  , S327-S328DOI: ( /j.bbmt ) Copyright © Terms and Conditions

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