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Cutaneous involvement in multiple myeloma mimicking acral-lentiginous melanoma  Antonio Martorell, MD, Fernando Millan-Parrilla, MD, Enrique Gimeno-Carpio,

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Presentation on theme: "Cutaneous involvement in multiple myeloma mimicking acral-lentiginous melanoma  Antonio Martorell, MD, Fernando Millan-Parrilla, MD, Enrique Gimeno-Carpio,"— Presentation transcript:

1 Cutaneous involvement in multiple myeloma mimicking acral-lentiginous melanoma 
Antonio Martorell, MD, Fernando Millan-Parrilla, MD, Enrique Gimeno-Carpio, MD  Journal of the American Academy of Dermatology  Volume 62, Issue 6, Pages (June 2010) DOI: /j.jaad Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 A and B, Indurated and ulcerated plaque with irregular brown-black borders affecting the ungueal matrix of the toe. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 A, Neoplastic infiltrate involving the entire dermis with an overlying ulcerated epidermis. B and C, Dermal infiltrate composed of large cells with pleomorphic nuclei, prominent nucleoli, and granular eosinophilic cytoplasm. D, Strong expression of CD138 establishes the plasmacyte lineage of the cells. (A-C, Hematoxylin–eosin stain; D, CD138 stain; original magnifications: A, ×25; B, ×50; C, ×100; D, ×50.) Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions


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