1. Chapter 3: Chromosome 3 3 A Cell Nucleus 125,188 bp 1444 aa
DNA Sequence
Chromosome
125,188 bp
Name of Protein 3
Name of Gene
Rho FTPase activating protein 31
ARHGAP31
transcription
Amino acid sequence
mRNA
1444 aa
Cytoplasm
translation
What does this protein make up or do?
A Cell
Nucleus
Condition/Disease
Adams-Oliver Syndrome

2. Description of Adams-Oliver Syndrome
Symptoms and characteristics
Absent phalanges/bones in the fingers and toes
The primary features are an abnormality in skin development (called aplasia cutis congenita) and malformations of the limbs. A variety of other features can occur in people with Adams-Oliver syndrome.
Hairless scarred patches of scalp
It usually appears at birth
In some cases, people with Adams-Oliver syndrome have neurological problems, such as developmental delay, learning disabilities, or abnormalities in the structure of the brain.
It’s inheritable

3. Description of Adams-Oliver Syndrome
Who is affected? Adams-Oliver syndrome is a rare disorder; its prevalence is unknown.
Outlook or quality of life I suppose that if a person was affected that they could lead a very difficult life but, a lot of patients develop neurological conditions that could lead to death but that’s only in some cases.
Researcher: ST

4. References http://chromosome3disorder.com/
Chromosome-3.aspx