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Updates on the Prevention and Management of CINV
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Topics Covered
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Types of CINV
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Emetogenic Potential of Regimens
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Patient-Related Risk Factors
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Why It Is Important to Prevent CINV
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What Does Prophylaxis Involve?
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Therapies for Preventing or Treating CINV
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Clinical Practice Guidelines for Preventing and Managing CINV
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MASCC Recommendations for Preventing Acute Nausea and Vomiting
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MASCC Recommendations for Delayed Nausea and Vomiting
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Challenges: Nonadherence to Practice Guidelines
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Clark-Snow et al Findings
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More Recently Approved Therapies
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Rolapitant: Schwartzberg et al
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Rolapitant: Schwartzberg et al (cont)
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Rolapitant: Rapoport et al
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Rolapitant: Navari et al
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Rolapitant: Aapro et al
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NEPA: Approval
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NEPA: Gralla et al Phase 3 Trial
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NEPA: Aapro et al Phase 3 Trial
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NEPA: Feyer et al
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NEPA: Aapro et al Post Hoc Safety Analysis
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Palonosetron in Triplet Regimen
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Palonosetron in Triplet Regimen (cont)
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Aprepitant: Kang et al
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Kang et al: CR Rate
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Olanzapine: Navari et al
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Navari et al Study Findings
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Navari et al Study Findings (cont)
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Olanzapine: Chiu et al
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APF530: A New 5-HT3 RA Formulation
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Updated Clinical Practice Guidelines
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Updated ASCO Guidelines
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Summary of Key Points
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Abbreviations
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Abbreviations (cont)
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