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Thermogenesis by THADA

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Presentation on theme: "Thermogenesis by THADA"— Presentation transcript:

1 Thermogenesis by THADA
Nirmalya Chatterjee, Norbert Perrimon  Developmental Cell  Volume 41, Issue 1, Pages 1-2 (April 2017) DOI: /j.devcel Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Non-shivering Thermogenesis Triggered by THADA
SERCA uses the energy of ATP hydrolysis to pump Ca2+ into the ER lumen. THADA uncouples ATP hydrolysis from Ca2+ transport, and that results in reduced Ca2+ transport into ER and in thermogenesis due to dissipation of the energy from ATP hydrolysis in the form of heat. Developmental Cell  , 1-2DOI: ( /j.devcel ) Copyright © 2017 Elsevier Inc. Terms and Conditions

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