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Emergence of community-associated methicillin-resistant Staphylococcus aureus strains in the neonatal intensive care unit: an infection prevention and.

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Presentation on theme: "Emergence of community-associated methicillin-resistant Staphylococcus aureus strains in the neonatal intensive care unit: an infection prevention and."— Presentation transcript:

1 Emergence of community-associated methicillin-resistant Staphylococcus aureus strains in the neonatal intensive care unit: an infection prevention and patient safety challenge  P.J. Reich, M.G. Boyle, P.G. Hogan, A.J. Johnson, M.A. Wallace, A.M. Elward, B.B. Warner, C.-A.D. Burnham, S.A. Fritz  Clinical Microbiology and Infection  Volume 22, Issue 7, Pages 645.e1-645.e8 (July 2016) DOI: /j.cmi Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

2 Fig. 1 Flow chart of participant selection. Patients transferred into the St Louis Children’s Hospital neonatal intensive care unit (SLCH NICU) from an outside hospital more than 48 hours after birth and colonized with methicillin-resistant Staphylococcus aureus upon admission to the SLCH NICU were not included in the full chart review, but the microbiology data for their isolates were included in the analysis. Clinical Microbiology and Infection  , 645.e1-645.e8DOI: ( /j.cmi ) Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

3 Fig. 2 Proportion of patients colonized in the anterior nares with healthcare-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) (SCCmec type II) and community-associated (CA-) MRSA (SCCmec types IV and V) strains by year in the neonatal intensive care unit. Clinical Microbiology and Infection  , 645.e1-645.e8DOI: ( /j.cmi ) Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

4 Fig. 3 (a) Overview of surveillance cultures of patients colonized with methicillin-resistant Staphylococcus aureus (MRSA) strains exhibiting mupirocin resistance (possessing the mupA gene). (b) Overview of surveillance cultures of patients colonized with MRSA strains exhibiting chlorhexidine resistance (possessing the qacA/B genes). Of the eight chlorhexidine-resistant isolates, three distinct strain types were identified, designated as A, B and C in the figure. Patient IDs NICU 21 and NICU 22 are twins. Clinical Microbiology and Infection  , 645.e1-645.e8DOI: ( /j.cmi ) Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions


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