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Irisin, Turning Up the Heat

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1 Irisin, Turning Up the Heat
Francesc Villarroya  Cell Metabolism  Volume 15, Issue 3, Pages (March 2012) DOI: /j.cmet Copyright © 2012 Elsevier Inc. Terms and Conditions

2 Figure 1 “Browning” Effect of Irisin in White Adipose Tissue
Irisin is released from skeletal muscle, especially after exercise. Irisin triggers the differentiation of precursor cells present within the white adipose tissue into cells with brown adipocyte characteristics such as high abundance of uncoupling protein-1, multilocular fat droplets, and mitochondria. Cell Metabolism  , DOI: ( /j.cmet ) Copyright © 2012 Elsevier Inc. Terms and Conditions

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