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Highlighting the impact of cascade carrier testing in cystic fibrosis families  Ingrid Duguépéroux, Carine L'Hostis, Marie-Pierre Audrézet, Gilles Rault,

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Presentation on theme: "Highlighting the impact of cascade carrier testing in cystic fibrosis families  Ingrid Duguépéroux, Carine L'Hostis, Marie-Pierre Audrézet, Gilles Rault,"— Presentation transcript:

1 Highlighting the impact of cascade carrier testing in cystic fibrosis families 
Ingrid Duguépéroux, Carine L'Hostis, Marie-Pierre Audrézet, Gilles Rault, Irène Frachon, Rémy Bernard, Philippe Parent, Martine Blayau, Sébastien Schmitt, Emmanuelle Génin, Claude Férec, Virginie Scotet  Journal of Cystic Fibrosis  Volume 15, Issue 4, Pages (July 2016) DOI: /j.jcf Copyright © 2016 European Cystic Fibrosis Society. Terms and Conditions

2 Fig. 1 Flow chart of the inclusion/exclusion criteria.
Journal of Cystic Fibrosis  , DOI: ( /j.jcf ) Copyright © 2016 European Cystic Fibrosis Society. Terms and Conditions

3 Fig. 2 A. Representation of time taken to be tested for relatives.
Time taken to be tested represents the difference between the date of testing and the date of family mutation identification (or the date at adulthood (18years) for relatives who were minor when the mutation was identified). B. Representation of age of relatives at testing. It should be noted that testing was performed before the age of 18years in 21 relatives, either because CF was suspected in siblings, or because testing was performed before the 1994 French Bioethics Laws that govern genetic testing management and prohibit testing of minor children. Journal of Cystic Fibrosis  , DOI: ( /j.jcf ) Copyright © 2016 European Cystic Fibrosis Society. Terms and Conditions

4 Fig. 3 Overview and public health implications of carrier testing in the 40 participating CF families. Journal of Cystic Fibrosis  , DOI: ( /j.jcf ) Copyright © 2016 European Cystic Fibrosis Society. Terms and Conditions


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