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Why We Should Put Clothes on Mice
Irfan J. Lodhi, Clay F. Semenkovich Cell Metabolism Volume 9, Issue 2, Pages (February 2009) DOI: /j.cmet Copyright © 2009 Elsevier Inc. Terms and Conditions
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Figure 1 UCP1 Deficiency and Thermoneutrality
UCP1 knockout mice maintained at room temperature (top panel in blue to represent a cold environment) activate UCP1-independent processes to maintain body temperature, an effect that obscures the role of UCP1 in bioenergetics. The same mice maintained at thermoneutrality (bottom panel in red to represent a warm environment) do not activate these processes and are susceptible to the development of obesity. Cell Metabolism 2009 9, DOI: ( /j.cmet ) Copyright © 2009 Elsevier Inc. Terms and Conditions
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