1. Supplementary figure1. CK7 CK20 CDX2 DPEP1 Cut off value: 85%
Overall accuracy: 76%
Cut off value: 10%
Overall accuracy: 64%
CDX2
DPEP1
Cut off value: 60%
Overall accuracy: 83%
Cut off value: 5%
Overall accuracy: 81%

2. Supplementary figure2. A. B. CK7 CK20 Metastasis of digestive organ
CK20 diffuse
CK20 patchy&negative
CK7 negative
CK7 positive
Tumor type n
Primary 46 1 45
digestive organ
colorectal 8 7
non-colorectal 11 10
Total 65 9 56
CK7
CK20
>5 ≦5
Metastasis of
digestive organ
(10/36)
Primary
(9/59)
Overall accuracy; 82% (74/90)
≦ 80
>80
(39/42)
Positive
diffuse type :>50% staining of tumor cells
patcy type :10-50%
Negative <10%
Overall accuracy; 82% (53/65)