1. Interstitial fluid homeostasis and pressure: news from the black box
Jens Titze 
Kidney International 
Volume 84, Issue 5, Pages (November 2013)
DOI: /ki
Copyright © 2013 International Society of Nephrology Terms and Conditions

2. Figure 1
Starling forces and their relevance for interstitial fluid and pressure homeostasis. Hydrostatic and colloid osmotic pressures are referred to as Starling forces. Capillary filtration pressures (P(c)) and interstitial colloid osmotic pressures (COP(if)) support transmembrane flux from the capillary into the interstitium, while interstitial fluid pressures (P(if)) and intra-capillary colloid osmotic pressures (COP(c)) lead to reabsorption of fluids. The original Starling equation has been modified and updated by capillary reflection coefficients, hydraulic permeability, and local interstitial protein gradients. Besides interstitial fluid content, tissue compliance is an important factor for the generation of interstitial pressure. Additional recent advances in understanding the molecular regulation of lymphangiogenesis provide new insights into outflow of filtrated interstitial fluid via the lymph capillary network. Background is an immunofluorescent view of real lymph vessels (green) and adjacent capillaries (red)
courtesy of Agnes Schröder, University of Erlangen.
Kidney International  , DOI: ( /ki )
Copyright © 2013 International Society of Nephrology Terms and Conditions