1. TIMI Myocardial Perfusion (TMP) Grades Dye strongly persistent
TMP Grade 0 or no perfusion of the myocardium was associated with the highest mortality (6.2%).
If a stain of the myocardium was present (TMPG 1) , mortality was also high at 5.1%. If dye was strongly
persistent at the end of the washout phase (TMPG 2), then mortality was 4.4%.
The lowest mortality was observed in those patients with normal TMP grade 3 perfusion where dye was
minimally persistent at the end of the washout phase and mortality was only 2.0%.
The 4 way p value was p=0.05.
Normal ground glass
appearance of blush
Dye mildly persistent
at end of washout
Dye strongly persistent
at end of washout
Gone by next injection
Stain present
Blush persists
on next injection
No or minimal blush
6.2%
5.1%
Mortality (%)
p = 0.05
4.4%
2.0%
n = 203
n = 46
n = 79
n = 434
Gibson et al, Circulation 2000