1. Quantamatrix Multiplexed Assay Platform system for direct detection of bacteria and antibiotic resistance determinants in positive blood culture bottles 
H.Y. Wang, Y. Uh, S. Kim, H. Lee 
Clinical Microbiology and Infection 
Volume 23, Issue 5, Pages 333.e1-333.e7 (May 2017)
DOI: /j.cmi
Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

2. Fig. 1
Processes of the Quantamatrix Multiplexed Assay Platform (QMAP) system. (a) Denatured PCR products mixed type-coded microdisks with graphical barcoded carboxyl-functionalized magnetic disks in a microwell plate. (b) Hybridization, washing, and R-phycoerythrin-conjugated streptavidin processes to produce fluorescent signals were analysed automatically. (c) QMAP analysis of the fluorescence intensity of all the microdisks in the image was automatically measured using the provided QMAP software (version 2.0) and was auto-interpreted with Microsoft Excel. Twelve fields of view (3 x-axis×4 y-axis) in one microwell were captured, and the average value of fluorescence intensity calculated. Positive fluorescence intensity signals (>500) for identification of GPB, GNB, and Candida spp., as well as identification of genes for antibiotic resistance, were automatically represented.
Clinical Microbiology and Infection  , 333.e1-333.e7DOI: ( /j.cmi )
Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

3. Fig. 2
Study design and sample distribution. SIRS, systemic inflammatory response syndrome; GPB, Gram-positive bacteria; GNB, Gram-negative bacteria; MRSA, methicillin-resistant Staphylococcus aureus; MRCoNS, methicillin-resistant coagulase-negative staphylococci; VRE, vancomycin-resistant enterococci; ESBL, extended spectrum β-lactamase.
Clinical Microbiology and Infection  , 333.e1-333.e7DOI: ( /j.cmi )
Copyright © 2016 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions