1. Redefining advanced maternal age as an indication for preimplantation genetic screening 
Miguel Milán, Ana Cristina Cobo, Lorena Rodrigo, Emilia Mateu, Amparo Mercader, Pilar Buendía, Vanessa Peinado, Arantzazu Delgado, Pere Mir, Carlos Simón, José Remohí, Antonio Pellicer, Carmen Rubio 
Reproductive BioMedicine Online 
Volume 21, Issue 5, Pages (November 2010)
DOI: /j.rbmo
Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

2. Figure 1
Chromosomal abnormalities found in embryos from advanced maternal age patients. (A) The percentage of abnormal embryos increased progressively with maternal age. (B) The percentage remained constant irrespective of the number of metaphase II (MII) oocytes retrieved after ovarian stimulation.
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

3. Figure 2
Clinical outcome according to maternal age. (A) The number of embryo transfers was significantly higher in patients 38 and 39years old in the non-PGS group when compared with the PGS group (P<0.05), but was comparable in patients ⩾40years old. (B) Improved ongoing implantation rates (IR) were observed in the PGS group, with higher differences in patients ⩾41years of age. (C) A trend towards higher ongoing pregnancy rate per oocyte retrieval (PR/OR) was observed for non-PGS groups in patients 38 and 39years of age, whereas a change of trend was observed from 40years onwards, with an improvement of ongoing pregnancy rate per oocyte retrieval with PGS. ∗P<0.0001, #P<0.05, †P<0.01.
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions