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The Role of Central and Peripheral Muscle Fatigue in Postcancer Fatigue: A Randomized Controlled Trial  Hetty Prinsen, PhD, Johannes P. van Dijk, PhD,

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Presentation on theme: "The Role of Central and Peripheral Muscle Fatigue in Postcancer Fatigue: A Randomized Controlled Trial  Hetty Prinsen, PhD, Johannes P. van Dijk, PhD,"— Presentation transcript:

1 The Role of Central and Peripheral Muscle Fatigue in Postcancer Fatigue: A Randomized Controlled Trial  Hetty Prinsen, PhD, Johannes P. van Dijk, PhD, Machiel J. Zwarts, MD, PhD, Jan Willem H. Leer, MD, PhD, Gijs Bleijenberg, PhD, Hanneke W.M. van Laarhoven, MD, PhD  Journal of Pain and Symptom Management  Volume 49, Issue 2, Pages (February 2015) DOI: /j.jpainsymman Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

2 Fig. 1 Flowchart of the study. CBT = cognitive behavioral therapy; CAF = central activation failure; MFCV = muscle fiber conduction velocity. Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman ) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

3 Fig. 2 (Panel a) Voluntary force, (Panel b) muscle fiber conduction velocity (MFCV), and (Panel c) central activation failure (CAF) during a two-minute sustained maximal voluntary contraction of the biceps brachii muscle of severely fatigued and non-fatigued disease-free cancer survivors. Data are presented as mean ± SEM. Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman ) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions

4 Fig. 3 (Panels a and b) Voluntary force. (Panels c and d) Muscle fiber conduction velocity (MFCV). (Panels e and f) Central activation failure (CAF) during a two-minute sustained maximal voluntary contraction of the biceps brachii muscle of severely fatigued disease-free cancer survivors (Panels a, c, and e) in the cognitive behavioral therapy (CBT) and (Panels b, d, and f) waiting list (WL) groups, both at baseline and follow-up. Data are presented as mean ± SEM. Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman ) Copyright © 2015 American Academy of Hospice and Palliative Medicine Terms and Conditions


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