1. Serum anti-PDIK1L autoantibody as a novel marker for endometriosis
Motowo Nabeta, M.D., Yasuhito Abe, M.D., Ryuma Haraguchi, Ph.D., Katsumi Kito, M.D., Yasuki Kusanagi, M.D., Masaharu Ito, M.D. 
Fertility and Sterility 
Volume 94, Issue 7, Pages e1 (December 2010)
DOI: /j.fertnstert
Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Identification of PDIK1L as an autoantigen in patients with endometriosis. (A) Western blotting using the serum of a healthy control (Ctrl) and an endometriotic patient (Endo). Seven major endometriosis-specific spots (A–G) were found. These spots were identified in the Coomassie brilliant blue (CBB)-stained 2D PAGE gel (A–G). (B) MASCOT analysis of spot D, which was identified as PDIK1L.
Fertility and Sterility  , e1DOI: ( /j.fertnstert )
Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

3. Figure 2
(A) Scatter plots of the serum anti-PDIK1L-autoAb (left) and CA125 (right) levels in healthy controls (H-ctrl), disease controls (D-ctrl), and endometriotic patients (Endo). Levels in the endometriotic patients were significantly elevated against healthy controls (P<.0001; Welch's t test) and disease controls (P<.0001). The cutoff levels are indicated in the figures at 300 and 35 U/mL for anti-PDIK1L-autoAb and CA125, respectively. (B) The positive and negative rates of anti-PDIK1L-auotAb (left) and CA125 (right) assays in diagnosis of endometriosis. (C) Scatter plots of the serum anti-PDIK1L-autoAb (left) and CA125 levels (right) according to the stage of endometriosis. The positive rates of anti-PDIK1L-autoAb (left) and CA125 (right) assays are shown at the bottom.
Fertility and Sterility  , e1DOI: ( /j.fertnstert )
Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions

4. Preliminary data of ELISAs for autoAbs against (A) PHD-finger protein 6, (B) β-actin, (C) cyclin D2, (D) β-galactosyltransferase, and (E) Rab32 proteins in healthy control, disease control, and patients with endometriosis. As shown, there was no statistically significant difference between controls and endometriotic patients in these assays.
Fertility and Sterility  , e1DOI: ( /j.fertnstert )
Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions