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Tissue Morphogenesis: Take a Step Back and Relax!
Petra Stockinger, Jérôme Solon Current Biology Volume 27, Issue 16, Pages R813-R815 (August 2017) DOI: /j.cub Copyright © 2017 Elsevier Ltd Terms and Conditions
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Figure 1 Tissue relaxation upon stretch by Step recruitment.
(A) Tissue response upon external stretch in wild-type Drosophila and in a step mutant. During stretch, cell–cell junctions reorganize to allow tissue elongation as a consequence of Step activity (middle). In absence of Step, cells are unable to reorganize, and multicellular rosettes form (right, in dark grey). (B) Step protein is recruited to actomyosin enrichments at junctions and vertices (left) and downregulates actomyosin activity (middle), which allows for junctional elongation (right). Current Biology , R813-R815DOI: ( /j.cub ) Copyright © 2017 Elsevier Ltd Terms and Conditions
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