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Genetic predictors of testosterone and their associations with cardiovascular disease and risk factors: A Mendelian randomization investigation  C. Mary.

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Presentation on theme: "Genetic predictors of testosterone and their associations with cardiovascular disease and risk factors: A Mendelian randomization investigation  C. Mary."— Presentation transcript:

1 Genetic predictors of testosterone and their associations with cardiovascular disease and risk factors: A Mendelian randomization investigation  C. Mary Schooling, Shan Luo, Shiu Lun Au Yeung, Deborah J. Thompson, Savita Karthikeyan, Thomas R. Bolton, Amy M. Mason, Erik Ingelsson, Stephen Burgess  International Journal of Cardiology  Volume 267, Pages (September 2018) DOI: /j.ijcard Copyright © 2018 The Authors Terms and Conditions

2 Fig. 1 Genetic associations with ischaemic stroke against genetic associations with testosterone. Genetic variants are those in the 10q21 (JMJD1C) gene region included in the stepwise selection score. Genetic associations with testosterone (per allele increase in log-transformed testosterone) were estimated in men only and are taken from Jin et al. [19]; genetic associations with ischaemic stroke risk (per allele log odds ratio) are taken from the UK Biobank and were estimated in men and women (left), men only (middle), and women only (right). International Journal of Cardiology  , DOI: ( /j.ijcard ) Copyright © 2018 The Authors Terms and Conditions


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