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Protecting Against Cocaine, Heroin, and Sarin Gas

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Presentation on theme: "Protecting Against Cocaine, Heroin, and Sarin Gas"— Presentation transcript:

1 Protecting Against Cocaine, Heroin, and Sarin Gas
Duncan McRee  Chemistry & Biology  Volume 10, Issue 4, Pages (April 2003) DOI: /S (03)

2 Figure 1 Compounds and Pathways that Involve Human Carboxylesterase 1 Are Arranged around the Trimeric Form of the Enzyme Chemistry & Biology  , DOI: ( /S (03) )

3 Figure 2 Human Carboxylesterase 1 Metabolizes Cocaine to Benzoylecgonine, and, When Alcohol Is Present, to Cocaethylene; the Enzyme Also Converts Heroin to Its Active Metabolite, Morphine Benzoylecgonine, cyan; cocaethylene, gold; morphine, green. Both figures were provided by S. Bencharit and M.R. Redinbo, UNC-Chapel Hill. Chemistry & Biology  , DOI: ( /S (03) )


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