1. Reproductive outcomes of testicular versus ejaculated sperm for intracytoplasmic sperm injection among men with high levels of DNA fragmentation in semen: systematic review and meta-analysis 
Sandro C. Esteves, M.D., Ph.D., Matheus Roque, M.D., Cara K. Bradley, Ph.D., Nicolás Garrido, Ph.D. 
Fertility and Sterility 
Volume 108, Issue 3, Pages e1 (September 2017)
DOI: /j.fertnstert
Copyright © 2017 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Flow chart for the trial identification and selection process.
Fertility and Sterility  , e1DOI: ( /j.fertnstert )
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3. Figure 2
Forest plot showing mean difference for sperm DNA fragmentation (SDF) rates between testicular and ejaculated sperm in men with high SDF, including subgroup analysis according to SDF assay (TUNEL and sperm chromatin dispersion [SCD]). CI = confidence interval; IV = inverse variance.
Fertility and Sterility  , e1DOI: ( /j.fertnstert )
Copyright © 2017 American Society for Reproductive Medicine Terms and Conditions

4. Figure 3
Forest plots showing odds ratios for (A) fertilization rates, (B) clinical pregnancy rates, (C) miscarriage rates, and (D) live birth rates with the use of intracytoplasmic sperm injection with testicular (Testi-ICSI) or ejaculated (Ejac-ICSI) sperm in men with high sperm DNA fragmentation, including subgroup analyses according to study population (repeated ICSI failure and non–ICSI failure) and semen analysis profile (oligozoospermia and normozoospermia). CI = confidence interval; IV = inverse variance.
Fertility and Sterility  , e1DOI: ( /j.fertnstert )
Copyright © 2017 American Society for Reproductive Medicine Terms and Conditions

5. Supplemental Figure 1
Funnel plots for the meta-analyses of sperm DNA fragmentation (SDF) rates between (A) ejaculated and testicular sperm and outcomes between intracytoplasmic sperm injection with testicular versus ejaculated sperm: (B) fertilization rates, (C) clinical pregnancy rates, (D) miscarriage rates, and (E) live birth rates.
Fertility and Sterility  , e1DOI: ( /j.fertnstert )
Copyright © 2017 American Society for Reproductive Medicine Terms and Conditions